Medical

An immortalized pluripotent human pancreatic ductal cell line which can (1)produce insulin for treating insulin dependent diabetes and (2)screen for the ability of a chemical to induce pancreatic stem cell differentiation or malignancy and (3)identify biomarkers for earlier diagnosis of pancreatic cancer.

Compositions and methods to develop epizootic catarrhal enteritis (ECE) therapeutics and diagnostic screening assays for use in ferrets.

Novel multi-substituted imidazolines that exhibit anti-microbial, anti-inflammatory and chemotherapy potentiator activity.

A modified yeast two-hybrid screening assay that can identify and distinguish different protein-protein interactions that rely upon different post-translational modification states.

This technology consists of unique indolazepine derivatives that inhibit NF-kB and cyclin-dependent kinases and have potential anti-inflammatory and anti-cancer activity. The invention describes the synthesis and demonstration of in vitro biological activity of these compounds.

This invention provides a method and handheld device for rapidly detecting microorganisms based upon a change of impedance as a result of the microorganism being bound between spaced interdigitated electrodes.

Novel multi-substituted imidazolines that exhibit anti-microbial, anti-inflammatory and chemotherapy potentiator activity as well as autoimmune disease and organ-rejection-inhibition application.

This technology is a patent-pending process for fabricating a reproducible lawn of carbon nanotubes (CNTs) on a semiconductor substrate using a microwave plasma Chemical Vapor Deposition (MPCVD) reactor chamber.

Rapid methods for detecting a nucleic acid's methylation status, which include endonucleases, PCR, and capillary electrophoresis, for use in diagnostic tests and therapeutic drug development.

The invention is a group of novel geldanamycin derivatives that have been developed with high specificity to Hsp90 in malaria parasites over humans. These derivatives represent a potential new therapeutic treatment for malaria.